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231225s2017 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.7b01431
|2 doi
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|a pubmed24n0909.xml
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|a (DE-627)NLM272962082
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|a (NLM)28617603
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Sae-Ung, Pornpen
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Antifouling Stripes Prepared from Clickable Zwitterionic Copolymers
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 23.01.2019
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|a Date Revised 23.01.2019
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a In this study, we have fabricated robust patterned surfaces that contain biocompatible and antifouling stripes, which cause microorganisms to consolidate into bare silicon spaces. Copolymers of methacryloyloxyethyl phosphorylcholine (MPC) and a methacrylate-substituted dihydrolipoic acid (DHLA) were spin-coated onto silicon substrates. The MPC units contributed biocompatibility and antifouling properties, and the DHLA units enabled cross-linking and the formation of robust thin films. Photolithography enabled the formation of 200-μm-wide poly(MPC-DHLA) stripped patterns that were characterized using atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), and rhodamine 6G staining. Regardless of the spacing between poly(MPC-DHLA) stripes (10, 50, or 100 μm), Escherichia coli rapidly adhered to the bare silicon gaps that lacked the copolymer, confirming the antifouling nature of MPC. Overall, this work provides a surface modification strategy for generating alternating biofouling and nonfouling surface structures that are potentially applicable for researchers studying cell biology, drug screening, and biosensor technology
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Research Support, U.S. Gov't, Non-P.H.S.
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7 |
|a Ions
|2 NLM
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|a Methacrylates
|2 NLM
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|a Polymers
|2 NLM
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|a Phosphorylcholine
|2 NLM
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|a 107-73-3
|2 NLM
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| 700 |
1 |
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|a Kolewe, Kristopher W
|e verfasserin
|4 aut
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1 |
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|a Bai, Ying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Rice, Eric W
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Schiffman, Jessica D
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Emrick, Todd
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hoven, Voravee P
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 33(2017), 28 vom: 18. Juli, Seite 7028-7035
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
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|g volume:33
|g year:2017
|g number:28
|g day:18
|g month:07
|g pages:7028-7035
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|u http://dx.doi.org/10.1021/acs.langmuir.7b01431
|3 Volltext
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