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231224s2017 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20170601-04
|2 doi
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|a pubmed24n0909.xml
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|a (NLM)28613352
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Khan, Mehnaz
|e verfasserin
|4 aut
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|a Comparison of Ranibizumab and Bevacizumab for Macular Edema Secondary to Retinal Vein Occlusions in Routine Clinical Practice
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 13.09.2017
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|a Date Revised 08.04.2022
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2017, SLACK Incorporated.
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|a BACKGROUND AND OBJECTIVE: To determine outcomes of intravitreal ranibizumab (IVR) (Lucentis; Genentech, South San Francisco, CA) versus bevacizumab (IVB) (Avastin; Genentech, South San Francisco, CA) for treatment of macular edema (ME) secondary to retinal vein occlusion (RVO) in routine clinical practice
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|a PATIENTS AND METHODS: A retrospective study identified treatment-naïve patients with ME secondary to RVO where treatment with either IVB or IVR was initiated. Retreatment criteria were based on ophthalmic examination and/or spectral-domain optical coherence tomography findings
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|a RESULTS: Central RVO/hemi-RVO cohort: At 12 months, change in visual acuity (VA) (IVR: +12.9 letters, IVB +6.9 letters; P = .53), central subfield thickness (CST) (IVR: -144.1 μm, IVB: -153.9 μm; P = .88), and number of injections (IVR: 5.40 injections, IVB: 5.64 injections; P = .70) were not different between groups. Branch RVO cohort: At 12-month follow-up, no differences in change in VA (IVR: +15.2 letters, IVB: +10.6 letters; P = .46), CST (IVR: -23.1 μm, IVB: -91.4 μm; P = .16), or number of injections (IVR: 5.93 injections, IVB: 5.13 injections; P = .15) were noted
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|a CONCLUSION: There is no notable difference in outcome between IVR and IVB when treating ME from RVO in routine clinical practice. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:465-472.]
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|a Journal Article
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|a Angiogenesis Inhibitors
|2 NLM
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|a Vascular Endothelial Growth Factor A
|2 NLM
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|a Bevacizumab
|2 NLM
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|a 2S9ZZM9Q9V
|2 NLM
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|a Ranibizumab
|2 NLM
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|a ZL1R02VT79
|2 NLM
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|a Wai, Karen M
|e verfasserin
|4 aut
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|a Silva, Fabiana Q
|e verfasserin
|4 aut
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|a Srivastava, Sunil
|e verfasserin
|4 aut
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|a Ehlers, Justis P
|e verfasserin
|4 aut
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|a Rachitskaya, Aleksandra
|e verfasserin
|4 aut
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|a Babiuch, Amy
|e verfasserin
|4 aut
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|a Deasy, Ryan
|e verfasserin
|4 aut
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|a Kaiser, Peter K
|e verfasserin
|4 aut
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|a Schachat, Andrew P
|e verfasserin
|4 aut
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|a Yuan, Alex
|e verfasserin
|4 aut
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|a Singh, Rishi P
|e verfasserin
|4 aut
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 48(2017), 6 vom: 01. Juni, Seite 465-472
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnns
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|g volume:48
|g year:2017
|g number:6
|g day:01
|g month:06
|g pages:465-472
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|u http://dx.doi.org/10.3928/23258160-20170601-04
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