Comparison of Ranibizumab and Bevacizumab for Macular Edema Secondary to Retinal Vein Occlusions in Routine Clinical Practice

Copyright 2017, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 48(2017), 6 vom: 01. Juni, Seite 465-472
1. Verfasser: Khan, Mehnaz (VerfasserIn)
Weitere Verfasser: Wai, Karen M, Silva, Fabiana Q, Srivastava, Sunil, Ehlers, Justis P, Rachitskaya, Aleksandra, Babiuch, Amy, Deasy, Ryan, Kaiser, Peter K, Schachat, Andrew P, Yuan, Alex, Singh, Rishi P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Angiogenesis Inhibitors Vascular Endothelial Growth Factor A Bevacizumab 2S9ZZM9Q9V Ranibizumab ZL1R02VT79
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245 1 0 |a Comparison of Ranibizumab and Bevacizumab for Macular Edema Secondary to Retinal Vein Occlusions in Routine Clinical Practice 
264 1 |c 2017 
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520 |a BACKGROUND AND OBJECTIVE: To determine outcomes of intravitreal ranibizumab (IVR) (Lucentis; Genentech, South San Francisco, CA) versus bevacizumab (IVB) (Avastin; Genentech, South San Francisco, CA) for treatment of macular edema (ME) secondary to retinal vein occlusion (RVO) in routine clinical practice 
520 |a PATIENTS AND METHODS: A retrospective study identified treatment-naïve patients with ME secondary to RVO where treatment with either IVB or IVR was initiated. Retreatment criteria were based on ophthalmic examination and/or spectral-domain optical coherence tomography findings 
520 |a RESULTS: Central RVO/hemi-RVO cohort: At 12 months, change in visual acuity (VA) (IVR: +12.9 letters, IVB +6.9 letters; P = .53), central subfield thickness (CST) (IVR: -144.1 μm, IVB: -153.9 μm; P = .88), and number of injections (IVR: 5.40 injections, IVB: 5.64 injections; P = .70) were not different between groups. Branch RVO cohort: At 12-month follow-up, no differences in change in VA (IVR: +15.2 letters, IVB: +10.6 letters; P = .46), CST (IVR: -23.1 μm, IVB: -91.4 μm; P = .16), or number of injections (IVR: 5.93 injections, IVB: 5.13 injections; P = .15) were noted 
520 |a CONCLUSION: There is no notable difference in outcome between IVR and IVB when treating ME from RVO in routine clinical practice. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:465-472.] 
650 4 |a Journal Article 
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650 7 |a Bevacizumab  |2 NLM 
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650 7 |a Ranibizumab  |2 NLM 
650 7 |a ZL1R02VT79  |2 NLM 
700 1 |a Wai, Karen M  |e verfasserin  |4 aut 
700 1 |a Silva, Fabiana Q  |e verfasserin  |4 aut 
700 1 |a Srivastava, Sunil  |e verfasserin  |4 aut 
700 1 |a Ehlers, Justis P  |e verfasserin  |4 aut 
700 1 |a Rachitskaya, Aleksandra  |e verfasserin  |4 aut 
700 1 |a Babiuch, Amy  |e verfasserin  |4 aut 
700 1 |a Deasy, Ryan  |e verfasserin  |4 aut 
700 1 |a Kaiser, Peter K  |e verfasserin  |4 aut 
700 1 |a Schachat, Andrew P  |e verfasserin  |4 aut 
700 1 |a Yuan, Alex  |e verfasserin  |4 aut 
700 1 |a Singh, Rishi P  |e verfasserin  |4 aut 
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