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231224s2017 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.6b04490
|2 doi
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|a pubmed24n0909.xml
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|a (NLM)28605903
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Tadepalli, Sirimuvva
|e verfasserin
|4 aut
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|a Influence of Surface Charge of the Nanostructures on the Biocatalytic Activity
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 23.07.2018
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|a Date Revised 23.07.2018
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a The physicochemical properties of abiotic nanostructures determine the structure and function of biological counterparts in biotic-abiotic nanohybrids. A comprehensive understanding of the interfacial interactions and the predictive capability of their structure and function is paramount for virtually all fields of bionanotechnology. In this study, using plasmonic nanostructures as a model abiotic system, we investigate the effect of the surface charge of nanostructures on the biocatalytic reaction kinetics of a bound enzyme. We found that the surface charge of nanostructures profoundly influences the structure, orientation, and activity of the bound enzyme. Furthermore, the interactions of the enzyme with nanoparticles result in stable conjugates that retain their functionality at elevated temperatures, unlike their free counterparts that lose their secondary structure and biocatalytic activity
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|a Journal Article
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|a Research Support, U.S. Gov't, Non-P.H.S.
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|a Wang, Zheyu
|e verfasserin
|4 aut
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|a Liu, Keng-Ku
|e verfasserin
|4 aut
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|a Jiang, Qisheng
|e verfasserin
|4 aut
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|a Slocik, Joseph
|e verfasserin
|4 aut
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|a Naik, Rajesh R
|e verfasserin
|4 aut
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|a Singamaneni, Srikanth
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 33(2017), 26 vom: 05. Juli, Seite 6611-6619
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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|g volume:33
|g year:2017
|g number:26
|g day:05
|g month:07
|g pages:6611-6619
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|u http://dx.doi.org/10.1021/acs.langmuir.6b04490
|3 Volltext
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