Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners
Neuropathic pain is relatively less responsive to opioids than other types of pain, which is possibly due to a disrupted opioid system partially caused by the profound microglial cell activation that underlines neuroinflammation. We demonstrated that intrathecally injected biphalin, a dimeric enkeph...
Veröffentlicht in: | Neural plasticity. - 1998. - 2017(2017) vom: 01., Seite 3829472 |
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Weitere Verfasser: | , , |
Format: | Online-Aufsatz |
Sprache: | English |
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2017
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Zugriff auf das übergeordnete Werk: | Neural plasticity |
Schlagworte: | Journal Article Enkephalins Inflammation Mediators Lipopolysaccharides Receptors, Opioid Nitric Oxide 31C4KY9ESH biphalin 83916-01-2 |
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