Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners

Neuropathic pain is relatively less responsive to opioids than other types of pain, which is possibly due to a disrupted opioid system partially caused by the profound microglial cell activation that underlines neuroinflammation. We demonstrated that intrathecally injected biphalin, a dimeric enkeph...

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Veröffentlicht in:Neural plasticity. - 1998. - 2017(2017) vom: 01., Seite 3829472
1. Verfasser: Popiolek-Barczyk, Katarzyna (VerfasserIn)
Weitere Verfasser: Piotrowska, Anna, Makuch, Wioletta, Mika, Joanna
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Enkephalins Inflammation Mediators Lipopolysaccharides Receptors, Opioid Nitric Oxide 31C4KY9ESH biphalin 83916-01-2