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231224s2017 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.7b00596
|2 doi
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|a pubmed25n0906.xml
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|a (DE-627)NLM271992751
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|a (NLM)28514855
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
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|a Fink, Lea
|e verfasserin
|4 aut
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|a Osmotic Stress Induced Desorption of Calcium Ions from Dipolar Lipid Membranes
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 23.01.2019
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|a Date Revised 23.01.2019
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The interaction between multivalent ions and lipid membranes with saturated tails and dipolar (net neutral) headgroups can lead to adsorption of the ions onto the membrane. The ions charge the membranes and contribute to electrostatic repulsion between them, in a similar manner to membranes containing charged lipids. Using solution X-ray scattering and the osmotic stress method, we measured and modeled the pressure-distance curves between partially charged membranes containing mixtures of charged (1,2-dilauroyl-sn-glycero-3-phospho-l-serine, DLPS) and dipolar (1,2-dilauroyl-sn-glycero-3-phosphocholine, DLPC) lipids over a wide range of membrane charge densities. We then compared these pressure-distance curves with those of DLPC membranes in the presence of 10 mM CaCl2. Our data and modeling show that when low osmotic stress is applied to the DLPC bilayers, the membrane charge density is equivalent to that of a charged membrane containing ca. 4 mol % DLPS and 96 mol % DLPC. As the osmotic stress increased, the charge density of the DLPC membrane decreased and resembled that of a membrane containing ca. 1 mol % DLPS. These data are consistent with desorption of the calcium ions from the DLPC membrane with increasing osmotic stress
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Cations
|2 NLM
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|a Lipid Bilayers
|2 NLM
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|a Lipids
|2 NLM
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|a Calcium
|2 NLM
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|a SY7Q814VUP
|2 NLM
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| 700 |
1 |
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|a Feitelson, Jehuda
|e verfasserin
|4 aut
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1 |
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|a Noff, Roy
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dvir, Tom
|e verfasserin
|4 aut
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|a Tamburu, Carmen
|e verfasserin
|4 aut
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| 700 |
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|a Raviv, Uri
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 33(2017), 23 vom: 13. Juni, Seite 5636-5641
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnas
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| 773 |
1 |
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|g volume:33
|g year:2017
|g number:23
|g day:13
|g month:06
|g pages:5636-5641
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|u http://dx.doi.org/10.1021/acs.langmuir.7b00596
|3 Volltext
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