Analysis of Trisiloxane Phosphocholine Bilayers

We have synthesized unique siloxane phosphocholines and characterized their aggregates in aqueous solution. The siloxane phosphocholines form nearly monodisperse vesicles in aqueous solution without the need for secondary extrusion processes. The area/lipid, lipid volume, and bilayer thickness were...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 33(2017), 20 vom: 23. Mai, Seite 4948-4953
1. Verfasser: Frampton, Mark B (VerfasserIn)
Weitere Verfasser: Marquardt, Drew, Letofsky-Papst, Ilse, Pabst, Georg, Zelisko, Paul M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Lipid Bilayers Siloxanes Unilamellar Liposomes Phosphorylcholine 107-73-3
Beschreibung
Zusammenfassung:We have synthesized unique siloxane phosphocholines and characterized their aggregates in aqueous solution. The siloxane phosphocholines form nearly monodisperse vesicles in aqueous solution without the need for secondary extrusion processes. The area/lipid, lipid volume, and bilayer thickness were determined from small-angle X-ray scattering experiments. The impetus for the spontaneous formation of unilamellar vesicles by these compounds is discussed
Beschreibung:Date Completed 23.01.2019
Date Revised 29.01.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/acs.langmuir.6b04162