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231224s2017 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20170329-03
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|a eng
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|a Regillo, Carl D
|e verfasserin
|4 aut
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|a Use of Corticosteroids in the Treatment of Patients With Diabetic Macular Edema Who Have a Suboptimal Response to Anti-VEGF
|b Recommendations of an Expert Panel
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|c 2017
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|a Text
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|a ƒaComputermedien
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|a Date Completed 02.05.2017
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|a Date Revised 19.12.2024
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|a published: Print
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|a Citation Status MEDLINE
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|a © 2017 Regillo, Callanan, Do, et al.
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|a BACKGROUND AND OBJECTIVE: Guidance on the use of corticosteroids in the treatment of diabetic macular edema (DME) is lacking. This study aimed to develop a clinically recommended treatment paradigm for DME with emphasis on the role of corticosteroids
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|a PATIENTS AND METHODS: An expert panel of nine retinal specialists in the United States developed consensus recommendations for DME treatment through a modified Delphi process
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|a RESULTS: The panelists typically use intravitreal injections of vascular endothelial growth factor (VEGF) antagonists as first-line treatment of DME and switch patients with an inadequate response to anti-VEGF therapy (failure of best-corrected visual acuity to improve to 20/40 or better because of edema after three to six monthly injections, or a less-than-50% reduction in excess macular thickness after three to four monthly injections) to intravitreal corticosteroid treatment
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|a CONCLUSION: Intravitreal corticosteroids have a potentially useful role in the treatment of patients with DME who have an inadequate response to intravitreal anti-VEGF therapy. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:291-301.]
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Angiogenesis Inhibitors
|2 NLM
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|a Glucocorticoids
|2 NLM
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|a Vascular Endothelial Growth Factor A
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1 |
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|a Callanan, David G
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1 |
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|a Do, Diana V
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| 700 |
1 |
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|a Fine, Howard F
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Holekamp, Nancy M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kuppermann, Baruch D
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Singer, Michael A
|e verfasserin
|4 aut
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| 700 |
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|a Singh, Rishi P
|e verfasserin
|4 aut
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 48(2017), 4 vom: 01. Apr., Seite 291-301
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