Design and Feasibility Study of a Single Photon Emission Microscope System for Small Animal I-125 Imaging

This paper presents a design study of a single photon emission microscope (SPEM) system for small animal imaging using I-125 labelled radiotracers. This system is based on the use of a very-high resolution gamma camera coupled to a converging non-multiplexing multiple pinhole collimator. This enable...

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Veröffentlicht in:IEEE transactions on nuclear science. - 1988. - 53(2006), 3 vom: 03. Juni, Seite 1168-1178
1. Verfasser: Meng, L J (VerfasserIn)
Weitere Verfasser: Clinthorne, N H, Skinner, S, Hay, R V, Gross, M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:IEEE transactions on nuclear science
Schlagworte:Journal Article Converging non-multiplexing multiple pinhole aperture microscope very-high spatial resolution gamma camera
Beschreibung
Zusammenfassung:This paper presents a design study of a single photon emission microscope (SPEM) system for small animal imaging using I-125 labelled radiotracers. This system is based on the use of a very-high resolution gamma camera coupled to a converging non-multiplexing multiple pinhole collimator. This enables one to "zoom" into a small local region inside the object to extract imaging information with a very high spatial resolution and a reasonable sensitivity for gamma rays emitted from this local region. The SPEM system also includes a pinhole (or multiple pinhole) gamma camera that has a full angular coverage of the entire object. The designed imaging spatial resolution for the SPEM system is between 250 μm to 500 μm FWHM
Beschreibung:Date Revised 24.03.2024
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:0018-9499
DOI:10.1109/TNS.2006.871405