Cytologic features of cutaneous follicular tumors and cysts in dogs
© 2017 American Society for Veterinary Clinical Pathology.
| Veröffentlicht in: | Veterinary clinical pathology. - 1975. - 46(2017), 1 vom: 01. März, Seite 143-150 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2017
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| Zugriff auf das übergeordnete Werk: | Veterinary clinical pathology |
| Schlagworte: | Journal Article Fine-needle aspiration cytology follicular cyst infundibular keratinizing acanthoma trichoblastoma trichoepithelioma |
| Zusammenfassung: | © 2017 American Society for Veterinary Clinical Pathology. BACKGROUND: Follicular tumors and cysts are common skin lesions in dogs. Both are distinguished based on their cellular origin (matrical, isthmus, or infundibular cells) and the type of keratin they produce. Typically, differentiation requires histopathology, as all these lesions often have similar cytologic features OBJECTIVES: The goal of this retrospective study was to identify unique cytologic features that may assist differentiation of canine benign follicular tumors and cysts at cytology, using histopathology as gold standard METHODS: Electronic medical records of the University of California-Davis Veterinary Medical Teaching Hospital were searched for diagnoses of follicular tumors and cysts in dogs that had both histopathologic and cytologic diagnoses between January 2000 and December 2013. Cytologic specimens were reassessed in a blinded manner for the presence and type of background, cells, noncellular elements, and inflammation RESULTS: Forty-six samples were included in the study. Follicular cysts (n = 25) and infundibular keratinizing acanthomas (n = 5) contained sheets of keratinized anucleate to nucleated squamous cells. Trichoepitheliomas (n = 8) had 2 primary cytologic presentations: those with primarily basaloid cells that appeared to be undergoing keratinization (3/8; 38%) and those with keratinizing anucleate to nucleated squamous cells (5/8; 63%). Trichoblastomas (n = 8) had pink matrix with spindle cells and contained cohesive clusters of basaloid cells CONCLUSION: Trichoblastomas, and to a lesser extent, trichoepitheliomas, have unique cytologic features with the potential to distinguish them from other benign follicular tumors and cysts. These results are an important first step toward improving the diagnostic specificity of cytologic examination of cutaneous follicular lesions |
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| Beschreibung: | Date Completed 26.09.2017 Date Revised 26.09.2017 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1939-165X |
| DOI: | 10.1111/vcp.12458 |