Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins : Tuning the Redox Potential with DNA

Escherichia coli endonuclease III (EndoIII) and MutY are DNA glycosylases that contain [4Fe4S] clusters and that serve to maintain the integrity of the genome after oxidative stress. Electrochemical studies on highly oriented pyrolytic graphite (HOPG) revealed that DNA binding by EndoIII leads to a...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 33(2017), 10 vom: 14. März, Seite 2523-2530
1. Verfasser: Bartels, Phillip L (VerfasserIn)
Weitere Verfasser: Zhou, Andy, Arnold, Anna R, Nuñez, Nicole N, Crespilho, Frank N, David, Sheila S, Barton, Jacqueline K
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Sulfur 70FD1KFU70 DNA 9007-49-2 Iron E1UOL152H7 DNA Glycosylases EC 3.2.2.-