Hydrophobic Nanoparticles Reduce the β-Sheet Content of SEVI Amyloid Fibrils and Inhibit SEVI-Enhanced HIV Infectivity

Semen-derived enhancer of virus infection (SEVI) fibrils are naturally abundant amyloid aggregates found in semen that facilitate viral attachment and internalization of human immunodeficiency virus (HIV) in cells, thereby increasing the probability of infection. Mature SEVI fibrils are composed of...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 33(2017), 10 vom: 14. März, Seite 2596-2602
1. Verfasser: Sheik, Daniel A (VerfasserIn)
Weitere Verfasser: Chamberlain, Jeffrey M, Brooks, Lauren, Clark, Melissa, Kim, Young Hun, Leriche, Geoffray, Kubiak, Clifford P, Dewhurst, Stephen, Yang, Jerry
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Amyloid