Post-translational modifications of FLOWERING LOCUS C modulate its activity

Flowering Locus C (FLC) is a key floral repressor that precisely controls flowering time. The role of FLC has been extensively studied at the transcriptional level using molecular biological and epigenetic approaches. However, how FLC functions and how its stability is controlled at the post-transla...

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Veröffentlicht in:Journal of experimental botany. - 1985. - 68(2017), 3 vom: 01. Jan., Seite 383-389
1. Verfasser: Kwak, Jun Soo (VerfasserIn)
Weitere Verfasser: Son, Ga Hyun, Song, Jong Tae, Seo, Hak Soo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Review Research Support, Non-U.S. Gov't FLC flowering phosphorylation post-translational modification sumoylation ubiquitination Arabidopsis Proteins mehr... At5g10140 protein, Arabidopsis MADS Domain Proteins
Beschreibung
Zusammenfassung:Flowering Locus C (FLC) is a key floral repressor that precisely controls flowering time. The role of FLC has been extensively studied at the transcriptional level using molecular biological and epigenetic approaches. However, how FLC functions and how its stability is controlled at the post-translational level are only beginning to be understood. Recent studies show that various post-translational modifications (PTMs) control the stability and activity of FLC. In this review, we focus on three types of PTMs that regulate FLC function: phosphorylation, ubiquitination, and sumoylation. This report should serve as a model to guide post-translational studies of other important floral regulators
Beschreibung:Date Completed 10.07.2018
Date Revised 03.01.2025
published: Print
Citation Status MEDLINE
ISSN:1460-2431
DOI:10.1093/jxb/erw431