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231224s2017 xx |||||o 00| ||eng c |
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|a 10.1093/jxb/erw499
|2 doi
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|a pubmed24n0896.xml
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|a eng
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|a Corratgé-Faillie, Claire
|e verfasserin
|4 aut
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|a Substrate (un)specificity of Arabidopsis NRT1/PTR FAMILY (NPF) proteins
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|c 2017
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 22.02.2018
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|a Date Revised 23.05.2018
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|a published: Print
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|a Citation Status MEDLINE
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|a © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.
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|a The conventional approach to categorizing transporters has been to class them according to their sequence homology, defining a 'family' (or a 'superfamily' if they are numerous), and according to their substrate specificity or selectivity. This general view is still relevant for some transporters, but it is being increasingly challenged. Here, we take the NRT1/PTR FAMILY (NPF) as one such example. NPF members do indeed display sequence and structural homologies with peptide transporter (PTR) proteins involved in the uptake of di- and tri-peptides in most other organisms. And in plants they were initially characterized as nitrate or peptide transporters. However, in recent years several other substrates have been identified, namely nitrite, chloride, glucosinolates, auxin (IAA), abscisic acid (ABA), jasmonates (JAs), and gibberellins (GAs). Some of these transporters are even capable of transporting more than one different substrate (e.g. nitrate/auxin, nitrate/ABA, nitrate/glucosinolates, or GA/JA). In this review, we give an overview of the substrate-specificity of the Arabidopsis NPF
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|a Journal Article
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|a Review
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|a Research Support, Non-U.S. Gov't
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|a Glucosinolate
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|a hormone
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|a nitrate
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|a nitrite
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|a peptide
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|a transporter
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|a Anion Transport Proteins
|2 NLM
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|a Arabidopsis Proteins
|2 NLM
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|a Lacombe, Benoît
|e verfasserin
|4 aut
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|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 68(2017), 12 vom: 01. Juni, Seite 3107-3113
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|x 1460-2431
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|g volume:68
|g year:2017
|g number:12
|g day:01
|g month:06
|g pages:3107-3113
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|u http://dx.doi.org/10.1093/jxb/erw499
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