A Difunctional Regeneration Scaffold for Knee Repair based on Aptamer-Directed Cell Recruitment

A Difunctional Regeneration Scaffold for Knee Repair based on Aptamer-Directed Cell Recruitment

© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 29(2017), 15 vom: 15. Apr.
1. Verfasser: Hu, Xiaoxia (VerfasserIn)
Weitere Verfasser: Wang, Yulan, Tan, Yaning, Wang, Jie, Liu, Haoyang, Wang, Yingqian, Yang, Shuang, Shi, Miusi, Zhao, Shiyong, Zhang, Yufeng, Yuan, Quan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article aptamers cell recruitment knee repair osteochondral defect scaffolds
Beschreibung
Zusammenfassung:© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
To solve the challenge of poor knee repair, an aptamer-bilayer scaffold is designed for autologous mesenchymal stem cell (MSC) recruitment and osteochondral regeneration. The scaffold can efficiently recruit MSCs to the defect and induce the directional differentiation of MSCs, thus successfully achieving simultaneous regeneration of cartilage and bone in the knee joint
Beschreibung:Date Completed 15.01.2019
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201605235