Validation of the OECD reproduction test guideline with the New Zealand mudsnail Potamopyrgus antipodarum using trenbolone and prochloraz

Validation of the OECD reproduction test guideline with the New Zealand mudsnail Potamopyrgus antipodarum using trenbolone and prochloraz

The Organisation for Economic Cooperation and Development (OECD) provides several standard test methods for the environmental hazard assessment of chemicals, mainly based on primary producers, arthropods, and fish. In April 2016, two new test guidelines with two mollusc species representing differen...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 26(2017), 3 vom: 06. Apr., Seite 370-382
1. Verfasser: Geiß, Cornelia (VerfasserIn)
Weitere Verfasser: Ruppert, Katharina, Askem, Clare, Barroso, Carlos, Faber, Daniel, Ducrot, Virginie, Holbech, Henrik, Hutchinson, Thomas H, Kajankari, Paula, Kinnberg, Karin Lund, Lagadic, Laurent, Matthiessen, Peter, Morris, Steve, Neiman, Maurine, Penttinen, Olli-Pekka, Sanchez-Marin, Paula, Teigeler, Matthias, Weltje, Lennart, Oehlmann, Jörg
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Endocrine disruption Fecundity Gastropod Mollusc Standardisation Toxicity Anabolic Agents Endocrine Disruptors Fungicides, Industrial mehr... Imidazoles Water Pollutants, Chemical prochloraz 99SFL01YCL Trenbolone Acetate RUD5Y4SV0S
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245 1 0 |a Validation of the OECD reproduction test guideline with the New Zealand mudsnail Potamopyrgus antipodarum using trenbolone and prochloraz 
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500 |a Date Revised 30.09.2020 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a The Organisation for Economic Cooperation and Development (OECD) provides several standard test methods for the environmental hazard assessment of chemicals, mainly based on primary producers, arthropods, and fish. In April 2016, two new test guidelines with two mollusc species representing different reproductive strategies were approved by OECD member countries. One test guideline describes a 28-day reproduction test with the parthenogenetic New Zealand mudsnail Potamopyrgus antipodarum. The main endpoint of the test is reproduction, reflected by the embryo number in the brood pouch per female. The development of a new OECD test guideline involves several phases including inter-laboratory validation studies to demonstrate the robustness of the proposed test design and the reproducibility of the test results. Therefore, a ring test of the reproduction test with P. antipodarum was conducted including eight laboratories with the test substances trenbolone and prochloraz and results are presented here. Most laboratories could meet test validity criteria, thus demonstrating the robustness of the proposed test protocol. Trenbolone did not have an effect on the reproduction of the snails at the tested concentration range (nominal: 10-1000 ng/L). For prochloraz, laboratories produced similar EC10 and NOEC values, showing the inter-laboratory reproducibility of results. The average EC10 and NOEC values for reproduction (with coefficient of variation) were 26.2 µg/L (61.7%) and 29.7 µg/L (32.9%), respectively. This ring test shows that the mudsnail reproduction test is a well-suited tool for use in the chronic aquatic hazard and risk assessment of chemicals 
650 4 |a Journal Article 
650 4 |a Endocrine disruption 
650 4 |a Fecundity 
650 4 |a Gastropod 
650 4 |a Mollusc 
650 4 |a Standardisation 
650 4 |a Toxicity 
650 7 |a Anabolic Agents  |2 NLM 
650 7 |a Endocrine Disruptors  |2 NLM 
650 7 |a Fungicides, Industrial  |2 NLM 
650 7 |a Imidazoles  |2 NLM 
650 7 |a Water Pollutants, Chemical  |2 NLM 
650 7 |a prochloraz  |2 NLM 
650 7 |a 99SFL01YCL  |2 NLM 
650 7 |a Trenbolone Acetate  |2 NLM 
650 7 |a RUD5Y4SV0S  |2 NLM 
700 1 |a Ruppert, Katharina  |e verfasserin  |4 aut 
700 1 |a Askem, Clare  |e verfasserin  |4 aut 
700 1 |a Barroso, Carlos  |e verfasserin  |4 aut 
700 1 |a Faber, Daniel  |e verfasserin  |4 aut 
700 1 |a Ducrot, Virginie  |e verfasserin  |4 aut 
700 1 |a Holbech, Henrik  |e verfasserin  |4 aut 
700 1 |a Hutchinson, Thomas H  |e verfasserin  |4 aut 
700 1 |a Kajankari, Paula  |e verfasserin  |4 aut 
700 1 |a Kinnberg, Karin Lund  |e verfasserin  |4 aut 
700 1 |a Lagadic, Laurent  |e verfasserin  |4 aut 
700 1 |a Matthiessen, Peter  |e verfasserin  |4 aut 
700 1 |a Morris, Steve  |e verfasserin  |4 aut 
700 1 |a Neiman, Maurine  |e verfasserin  |4 aut 
700 1 |a Penttinen, Olli-Pekka  |e verfasserin  |4 aut 
700 1 |a Sanchez-Marin, Paula  |e verfasserin  |4 aut 
700 1 |a Teigeler, Matthias  |e verfasserin  |4 aut 
700 1 |a Weltje, Lennart  |e verfasserin  |4 aut 
700 1 |a Oehlmann, Jörg  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Ecotoxicology (London, England)  |d 1992  |g 26(2017), 3 vom: 06. Apr., Seite 370-382  |w (DE-627)NLM098212214  |x 1573-3017  |7 nnns 
773 1 8 |g volume:26  |g year:2017  |g number:3  |g day:06  |g month:04  |g pages:370-382 
856 4 0 |u http://dx.doi.org/10.1007/s10646-017-1770-y  |3 Volltext 
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