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231224s2017 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201605754
|2 doi
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|a eng
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1 |
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|a Li, Chunyan
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Engineered Multifunctional Nanomedicine for Simultaneous Stereotactic Chemotherapy and Inhibited Osteolysis in an Orthotopic Model of Bone Metastasis
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|c 2017
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|a Text
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|a ƒaComputermedien
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|a Date Completed 11.10.2018
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A novel multifunctional Ag2 S quantum dot (QD)-based nanomedicine of alendronate (Ald)/doxorubicin (DOX)Ag2 S is developed for highly effective bone tumor therapy in an orthotopic model. The bone-targeting and osteolysis inhibition of Ald and the chemotherapeutic effect of DOX on the bone tumor are in situ visualized by Ag2 S QDs with emission in the second near-infrared window
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|a bone metastasis
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|a molecular imaging
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|a osteolysis inhibition
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|a targeted drug delivery
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4 |
|a tumor chemotherapy
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|a Antineoplastic Agents
|2 NLM
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| 650 |
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|a Silver Compounds
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|a Doxorubicin
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|a silver sulfide
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|a Alendronate
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| 650 |
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7 |
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| 700 |
1 |
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|a Zhang, Yejun
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1 |
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|a Chen, Guangcun
|e verfasserin
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| 700 |
1 |
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|a Hu, Feng
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| 700 |
1 |
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|a Zhao, Kui
|e verfasserin
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| 700 |
1 |
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|a Wang, Qiangbin
|e verfasserin
|4 aut
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