Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation

Hair cells (HCs) are the sensory preceptor cells in the inner ear, which play an important role in hearing and balance. The HCs of organ of Corti are susceptible to noise, ototoxic drugs, and infections, thus resulting in permanent hearing loss. Recent approaches of HCs regeneration provide new dire...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Neural plasticity. - 1998. - 2016(2016) vom: 25., Seite 2523458
1. Verfasser: Lu, Xiaoling (VerfasserIn)
Weitere Verfasser: Shu, Yilai, Tang, Mingliang, Li, Huawei
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Review
LEADER 01000naa a22002652 4500
001 NLM26831022X
003 DE-627
005 20231224222424.0
007 cr uuu---uuuuu
008 231224s2016 xx |||||o 00| ||eng c
024 7 |a 10.1155/2016/2523458  |2 doi 
028 5 2 |a pubmed24n0894.xml 
035 |a (DE-627)NLM26831022X 
035 |a (NLM)28119785 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Lu, Xiaoling  |e verfasserin  |4 aut 
245 1 0 |a Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation 
264 1 |c 2016 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 26.10.2017 
500 |a Date Revised 13.11.2018 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a Hair cells (HCs) are the sensory preceptor cells in the inner ear, which play an important role in hearing and balance. The HCs of organ of Corti are susceptible to noise, ototoxic drugs, and infections, thus resulting in permanent hearing loss. Recent approaches of HCs regeneration provide new directions for finding the treatment of sensor neural deafness. To have normal hearing function, the regenerated HCs must be reinnervated by nerve fibers and reform ribbon synapse with the dendrite of spiral ganglion neuron through nerve regeneration. In this review, we discuss the research progress in HC regeneration, the synaptic plasticity, and the reinnervation of new regenerated HCs in mammalian inner ear 
650 4 |a Journal Article 
650 4 |a Review 
700 1 |a Shu, Yilai  |e verfasserin  |4 aut 
700 1 |a Tang, Mingliang  |e verfasserin  |4 aut 
700 1 |a Li, Huawei  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Neural plasticity  |d 1998  |g 2016(2016) vom: 25., Seite 2523458  |w (DE-627)NLM098558390  |x 1687-5443  |7 nnns 
773 1 8 |g volume:2016  |g year:2016  |g day:25  |g pages:2523458 
856 4 0 |u http://dx.doi.org/10.1155/2016/2523458  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_21 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 2016  |j 2016  |b 25  |h 2523458