Hydrogels with Lotus Leaf Topography : Investigating Surface Properties and Cell Adhesion

The interactions of cells with the surface of materials is known to be influenced by a range of factors that include chemistry and roughness; however, it is often difficult to probe these factors individually without also changing the others. Here we investigate the role of roughness on cell adhesio...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 33(2017), 2 vom: 17. Jan., Seite 485-493
1. Verfasser: Santander-Borrego, Miriem (VerfasserIn)
Weitere Verfasser: Taran, Elena, Shadforth, Audra M A, Whittaker, Andrew K, Chirila, Traian V, Blakey, Idriss
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Hydrogels Polyhydroxyethyl Methacrylate 25249-16-5
LEADER 01000naa a22002652 4500
001 NLM267702493
003 DE-627
005 20231224221248.0
007 cr uuu---uuuuu
008 231224s2017 xx |||||o 00| ||eng c
024 7 |a 10.1021/acs.langmuir.6b03547  |2 doi 
028 5 2 |a pubmed24n0892.xml 
035 |a (DE-627)NLM267702493 
035 |a (NLM)28054787 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Santander-Borrego, Miriem  |e verfasserin  |4 aut 
245 1 0 |a Hydrogels with Lotus Leaf Topography  |b Investigating Surface Properties and Cell Adhesion 
264 1 |c 2017 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 24.09.2018 
500 |a Date Revised 02.12.2018 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a The interactions of cells with the surface of materials is known to be influenced by a range of factors that include chemistry and roughness; however, it is often difficult to probe these factors individually without also changing the others. Here we investigate the role of roughness on cell adhesion while maintaining the same underlying chemistry. This was achieved by using a polymerization in mold technique to prepare poly(hydroxymethyl methacrylate) hydrogels with either a flat topography or a topography that replicated the microscale features of lotus leaves. These materials were then assessed for cell adhesion, and atomic force microscopy and contact angle analysis were then used to probe the physical reasons for the differing behavior in relation to cell adhesion 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Hydrogels  |2 NLM 
650 7 |a Polyhydroxyethyl Methacrylate  |2 NLM 
650 7 |a 25249-16-5  |2 NLM 
700 1 |a Taran, Elena  |e verfasserin  |4 aut 
700 1 |a Shadforth, Audra M A  |e verfasserin  |4 aut 
700 1 |a Whittaker, Andrew K  |e verfasserin  |4 aut 
700 1 |a Chirila, Traian V  |e verfasserin  |4 aut 
700 1 |a Blakey, Idriss  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 33(2017), 2 vom: 17. Jan., Seite 485-493  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:33  |g year:2017  |g number:2  |g day:17  |g month:01  |g pages:485-493 
856 4 0 |u http://dx.doi.org/10.1021/acs.langmuir.6b03547  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 33  |j 2017  |e 2  |b 17  |c 01  |h 485-493