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231224s2017 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.6b03547
|2 doi
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|a eng
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|a Santander-Borrego, Miriem
|e verfasserin
|4 aut
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|a Hydrogels with Lotus Leaf Topography
|b Investigating Surface Properties and Cell Adhesion
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 24.09.2018
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|a Date Revised 02.12.2018
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The interactions of cells with the surface of materials is known to be influenced by a range of factors that include chemistry and roughness; however, it is often difficult to probe these factors individually without also changing the others. Here we investigate the role of roughness on cell adhesion while maintaining the same underlying chemistry. This was achieved by using a polymerization in mold technique to prepare poly(hydroxymethyl methacrylate) hydrogels with either a flat topography or a topography that replicated the microscale features of lotus leaves. These materials were then assessed for cell adhesion, and atomic force microscopy and contact angle analysis were then used to probe the physical reasons for the differing behavior in relation to cell adhesion
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Hydrogels
|2 NLM
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|a Polyhydroxyethyl Methacrylate
|2 NLM
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|a 25249-16-5
|2 NLM
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|a Taran, Elena
|e verfasserin
|4 aut
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|a Shadforth, Audra M A
|e verfasserin
|4 aut
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|a Whittaker, Andrew K
|e verfasserin
|4 aut
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|a Chirila, Traian V
|e verfasserin
|4 aut
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|a Blakey, Idriss
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 33(2017), 2 vom: 17. Jan., Seite 485-493
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|x 1520-5827
|7 nnns
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|g volume:33
|g year:2017
|g number:2
|g day:17
|g month:01
|g pages:485-493
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|u http://dx.doi.org/10.1021/acs.langmuir.6b03547
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