Sublimation-like Behavior of Cardiac Dynamics in Heart Failure : A Malignant Phase Transition?

An abrupt transition from sinus cardiac rhythm to atrial fibrillation (AF) is common in patients with chronic heart failure (CHF). We propose a conceptual framework for viewing this malignant transition in terms of a type of sublimation marked by the switch from highly periodic sinus interbeat inter...

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Veröffentlicht in:Complexity. - 1998. - 21(2016), Suppl 2 vom: 07. Nov., Seite 24-32
1. Verfasser: Goldberger, Ary L (VerfasserIn)
Weitere Verfasser: Henriques, Teresa, Mariani, Sara
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Complexity
Schlagworte:Journal Article atrial fibrillation entropy heart failure phase transition sublimation
Beschreibung
Zusammenfassung:An abrupt transition from sinus cardiac rhythm to atrial fibrillation (AF) is common in patients with chronic heart failure (CHF). We propose a conceptual framework for viewing this malignant transition in terms of a type of sublimation marked by the switch from highly periodic sinus interbeat interval dynamics characteristic of CHF to a state of random disorganization with AF. Sublimation of physical substances involves an increase in entropy via heat transfer. In contrast, the disease-related sublimation-like behavior involves a loss of information content, associated decreases in cardiac bioenergetic capacity and in multiscale entropy
Beschreibung:Date Revised 01.10.2020
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1076-2787
DOI:10.1002/cplx.21811