Competitive and Synergistic Interactions between Polymer Micelles, Drugs, and Cyclodextrins The Importance of Drug Solubilization Locus

Competitive and Synergistic Interactions between Polymer Micelles, Drugs, and Cyclodextrins : The Importance of Drug Solubilization Locus

Polymeric micelles, in particular PEO-PPO-based Pluronic, have emerged as promising drug carriers, while cyclodextrins (CD), cyclic oligosaccharides with an apolar cavity, have long been used for their capacity to form inclusion complexes with drugs. Dimethylated β-cyclodextrin (DIMEB) has the capac...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 32(2016), 49 vom: 13. Dez., Seite 13174-13186
1. Verfasser: Valero, Margarita (VerfasserIn)
Weitere Verfasser: Castiglione, Franca, Mele, Andrea, da Silva, Marcelo A, Grillo, Isabelle, González-Gaitano, Gustavo, Dreiss, Cécile A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Cyclodextrins Micelles Pharmaceutical Preparations Poloxamer 106392-12-5 Naproxen 57Y76R9ATQ Lidocaine mehr... 98PI200987 Pentobarbital I4744080IR Sodium Salicylate WIQ1H85SYP