Spontaneous Vesiculation and pH-Induced Disassembly of a Lysosomotropic Detergent : Impacts on Lysosomotropism and Lysosomal Delivery
Lysosomotropic detergents (LDs) selectively rupture lysosomal membranes through mechanisms that have yet to be characterized. A consensus view, currently, holds that LDs, which are weakly basic, diffuse across cellular membranes as monomers in an uncharged state, and via protonation in the acidic ly...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 32(2016), 50 vom: 20. Dez., Seite 13566-13575 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Amides Detergents O-methyl-serine dodecylamide hydrochloride Serine 452VLY9402 |