An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo

An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 29(2017), 6 vom: 05. Feb.
1. Verfasser: Sun, Wen (VerfasserIn)
Weitere Verfasser: Li, Shuyi, Häupler, Bernhard, Liu, Juan, Jin, Shubin, Steffen, Werner, Schubert, Ulrich S, Butt, Hans-Jürgen, Liang, Xing-Jie, Wu, Si
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article metallodrugs photochemotherapy photodynamic therapy polymers ruthenium Photosensitizing Agents Ruthenium 7UI0TKC3U5
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
An amphiphilic Ru-containing block copolymer is used as a photoactivated polymetallodrug for anticancer phototherapy. The block copolymer self-assembles into nanoparticles, which can accumulate at tumor sites in a mouse model. Red light irradiation of the block copolymer nanoparticles releases anticancer Ru complexes and generates cytotoxic 1 O2 , both of which can inhibit tumor growth
Beschreibung:Date Completed 15.01.2019
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201603702