Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes

Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder : A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes

Our hypothesis is that allosteric receptor-receptor interactions in homo- and heteroreceptor complexes may form the molecular basis of learning and memory. This principle is illustrated by showing how cocaine abuse can alter the adenosine A2AR-dopamine D2R heterocomplexes and their receptor-receptor...

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Veröffentlicht in:Neural plasticity. - 1998. - 2016(2016) vom: 08., Seite 4827268
1. Verfasser: Borroto-Escuela, Dasiel O (VerfasserIn)
Weitere Verfasser: Wydra, Karolina, Pintsuk, Julia, Narvaez, Manuel, Corrales, Fidel, Zaniewska, Magdalena, Agnati, Luigi F, Franco, Rafael, Tanganelli, Sergio, Ferraro, Luca, Filip, Malgorzata, Fuxe, Kjell
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Review Research Support, Non-U.S. Gov't Purinergic P1 Receptor Agonists Receptor, Adenosine A2A Receptors, Dopamine D2 Cocaine I5Y540LHVR