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|a 10.1109/TIP.2016.2624198
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|a DE-627
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|a eng
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|a Farag, Amal
|e verfasserin
|4 aut
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|a A Bottom-Up Approach for Pancreas Segmentation Using Cascaded Superpixels and (Deep) Image Patch Labeling
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|c 2017
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Revised 20.11.2019
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a Robust organ segmentation is a prerequisite for computer-aided diagnosis, quantitative imaging analysis, pathology detection, and surgical assistance. For organs with high anatomical variability (e.g., the pancreas), previous segmentation approaches report low accuracies, compared with well-studied organs, such as the liver or heart. We present an automated bottom-up approach for pancreas segmentation in abdominal computed tomography (CT) scans. The method generates a hierarchical cascade of information propagation by classifying image patches at different resolutions and cascading (segments) superpixels. The system contains four steps: 1) decomposition of CT slice images into a set of disjoint boundary-preserving superpixels; 2) computation of pancreas class probability maps via dense patch labeling; 3) superpixel classification by pooling both intensity and probability features to form empirical statistics in cascaded random forest frameworks; and 4) simple connectivity based post-processing. Dense image patch labeling is conducted using two methods: efficient random forest classification on image histogram, location and texture features; and more expensive (but more accurate) deep convolutional neural network classification, on larger image windows (i.e., with more spatial contexts). Over-segmented 2-D CT slices by the simple linear iterative clustering approach are adopted through model/parameter calibration and labeled at the superpixel level for positive (pancreas) or negative (non-pancreas or background) classes. The proposed method is evaluated on a data set of 80 manually segmented CT volumes, using six-fold cross-validation. Its performance equals or surpasses other state-of-the-art methods (evaluated by "leave-one-patient-out"), with a dice coefficient of 70.7% and Jaccard index of 57.9%. In addition, the computational efficiency has improved significantly, requiring a mere 6 ~ 8 min per testing case, versus ≥ 10 h for other methods. The segmentation framework using deep patch labeling confidences is also more numerically stable, as reflected in the smaller performance metric standard deviations. Finally, we implement a multi-atlas label fusion (MALF) approach for pancreas segmentation using the same data set. Under six-fold cross-validation, our bottom-up segmentation method significantly outperforms its MALF counterpart: 70.7±13.0% versus 52.51±20.84% in dice coefficients
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|a Journal Article
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|a Le Lu
|e verfasserin
|4 aut
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|a Roth, Holger R
|e verfasserin
|4 aut
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|a Liu, Jiamin
|e verfasserin
|4 aut
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|a Turkbey, Evrim
|e verfasserin
|4 aut
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|a Summers, Ronald M
|e verfasserin
|4 aut
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|i Enthalten in
|t IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
|d 1992
|g 26(2017), 1 vom: 04. Jan., Seite 386-399
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|x 1941-0042
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|g volume:26
|g year:2017
|g number:1
|g day:04
|g month:01
|g pages:386-399
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|u http://dx.doi.org/10.1109/TIP.2016.2624198
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