ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain Barrier In Vitro
Disruption of blood-brain barrier (BBB) follows brain trauma or central nervous system (CNS) stress. However, the mechanisms leading to this process or the underlying neural plasticity are not clearly known. We hypothesized that ATP/P2X7R signaling regulates the integrity of BBB. Activation of P2X7...
| Publié dans: | Neural plasticity. - 1998. - 2016(2016) vom: 24., Seite 8928530 |
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| Auteur principal: | |
| Autres auteurs: | , , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2016
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| Accès à la collection: | Neural plasticity |
| Sujets: | Journal Article Interleukin-1beta P2RX7 protein, human Purinergic P2X Receptor Antagonists Receptors, Purinergic P2X7 Tight Junction Proteins Adenosine Triphosphate 8L70Q75FXE MMP9 protein, human EC 3.4.24.35 |