Cyclization Improves Membrane Permeation by Antimicrobial Peptoids

Cyclization Improves Membrane Permeation by Antimicrobial Peptoids

The peptidomimetic approach has emerged as a powerful tool for overcoming the inherent limitations of natural antimicrobial peptides, where the therapeutic potential can be improved by increasing the selectivity and bioavailability. Restraining the conformational flexibility of a molecule may reduce...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 32(2016), 48 vom: 06. Dez., Seite 12905-12913
1. Verfasser: Andreev, Konstantin (VerfasserIn)
Weitere Verfasser: Martynowycz, Michael W, Ivankin, Andrey, Huang, Mia L, Kuzmenko, Ivan, Meron, Mati, Lin, Binhua, Kirshenbaum, Kent, Gidalevitz, David
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Anti-Bacterial Agents Peptoids