Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect

OBJECTIVE: Based on rapid advancement of genetic modification techniques, genomic editing is expected to become the most efficient tool for improvement of economic traits in livestock as well as poultry. In this study, we examined and verified the nickase of mutated CRISPR-associated protein 9 (Cas9...

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Bibliographische Detailangaben
Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 30(2017), 5 vom: 30. Mai, Seite 743-748
1. Verfasser: Lee, Jeong Hyo (VerfasserIn)
Weitere Verfasser: Kim, Si Won, Park, Tae Sub
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Cas9 Genome Editing Knockout Myostatin Nickase Poultry