Fabrication of RNA 3D Nanoprisms for Loading and Protection of Small RNAs and Model Drugs

Fabrication of RNA 3D Nanoprisms for Loading and Protection of Small RNAs and Model Drugs

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 45 vom: 15. Dez., Seite 10079-10087
1. Verfasser: Khisamutdinov, Emil F (VerfasserIn)
Weitere Verfasser: Jasinski, Daniel L, Li, Hui, Zhang, Kaiming, Chiu, Wah, Guo, Peixuan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article RNA drug encapsulation RNA nanocontainers nanobiotechnology nanotechnology pRNA 3WJ motif Pharmaceutical Preparations Proteins RNA 63231-63-0
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Constructing containers with defined shape and size to load and protect therapeutics and subsequently control their release in the human body has long been a dream. The fabrication of 3D RNA prisms, characterized by atomic force microscopy, cryo-electron microscopy, dynamic light scattering, and polyacrylamide gel electrophoresis, is reported for the loading and protection of small molecules, proteins, small RNA molecules, and their controlled release
Beschreibung:Date Completed 17.09.2018
Date Revised 12.11.2023
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201603180