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|a eng
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| 100 |
1 |
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|a Stafford, Randall B
|e verfasserin
|4 aut
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| 245 |
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|a An Actively Decoupled Dual Transceiver Coil System for Continuous ASL at 7 T
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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|a Date Revised 01.10.2020
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a 7 T arterial spin labeling (ASL) faces major challenges including the increased specific absorption rate (SAR) and increased B0 and B1 inhomogeneity. This work describes the design and implementation of a dual-coil system that allows for continuous ASL (CASL) at 7 T. This system consisted of an actively detunable eight-channel transceiver head coil, and a three-channel transceiver labeling coil. Four experiments were performed in 5 healthy subjects: (i) to demonstrate that active detuning during ASL labeling reduces magnetization transfer; (ii) to measure the B1 profile at the labeling plane; (iii) to quantify B0 off-resonance at the labeling plane; and (iv) to collect in vivo CASL data. The magnetization transfer ratio in the head coil was reduced to 0.0 ± 0.2% by active detuning during labeling. The measured B1 profiles in all 5 subjects were sufficient to satisfy the flow-driven adiabatic inversion necessary for CASL, however the actual labeling efficiency was significantly impacted by B0 off-resonance at the labeling plane. The measured CASL percent signal change in gray matter (0.94% ± 0.10%) corresponds with the low labeling efficiency predicted by the B0 off-resonance. This work demonstrates progress in the technical implementation of 7 T CASL, and reinforces the need for improved B0 homogeneity at the labeling plane
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|a Journal Article
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|a 7 T
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| 650 |
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|a B0-mapping
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| 650 |
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4 |
|a B1-mapping
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| 650 |
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|a arterial spin labeling
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| 650 |
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4 |
|a labeling coils
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| 650 |
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|a magnetic resonance imaging
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| 650 |
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4 |
|a specific absorption rate
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| 700 |
1 |
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|a Woo, Myung-Kyun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Oh, Se-Hong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dolui, Sudipto
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, Tiejun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kim, Young-Bo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Detre, John A
|e verfasserin
|4 aut
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| 700 |
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|a Cho, Zang-Hee
|e verfasserin
|4 aut
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| 700 |
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|a Lee, Jongho
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t International journal of imaging systems and technology
|d 1990
|g 26(2016), 2 vom: 02. Juni, Seite 106-115
|w (DE-627)NLM098193090
|x 0899-9457
|7 nnas
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| 773 |
1 |
8 |
|g volume:26
|g year:2016
|g number:2
|g day:02
|g month:06
|g pages:106-115
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|d 26
|j 2016
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|h 106-115
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