Arterial stiffness in metabolic syndrome

UNLABELLED: Arterial stiffness is increasingly recognized as an important determinant of cardiovascular risk and may be directly involved in the process of atherosclerosis. As atherosclerosis leads to increased arterial resistance and decrease the flow propagation speed within the arterial lumen, a...

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Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 28(2016), 4 vom: 28. Okt., Seite 249-56
1. Verfasser: Adel, Mona (VerfasserIn)
Weitere Verfasser: ELSheikh, Ayman, Sameer, Sameh, Haseeb, Waiel, ELSheikh, Eman, Kheder, Lamia
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article ALT, alanine transaminase AST, aspartate transaminase AVP AVP, aortic velocity propagation Aortic propagation velocity Arterial stiffness CRP, C reactive protein DBP, diastolic blood pressure E/e′, filling pressure mehr... EPF, epicardial fat FBS, fasting blood sugar FMD, flow mediated dilatation HDL, high density lipoprotein IVS, interventricular septum Metabolic syndrome SBP, systolic blood pressure TC, total cholesterol TG, triglycerides UA, uric acid WC, waist circumference
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245 1 0 |a Arterial stiffness in metabolic syndrome 
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520 |a UNLABELLED: Arterial stiffness is increasingly recognized as an important determinant of cardiovascular risk and may be directly involved in the process of atherosclerosis. As atherosclerosis leads to increased arterial resistance and decrease the flow propagation speed within the arterial lumen, a similar decrease in aortic flow propagation with increased downstream resistance is detected, so aortic flow propagation velocity AVP was evaluated in many studies as a new parameter of aortic stiffness 
520 |a AIM: To measure arterial stiffness using the new parameter AVP and compare it to flow mediated dilatation FMD as a parameter of endothelial dysfunction in patients with metabolic syndrome MS 
520 |a METHODS: AVP (assessed by transthoracic echocardiography) and FMD (assessed by brachial artery reactivity test) were measured in 100 patients with MS (Group 1) and were compared to 14 normal subjects (Group 2) 
520 |a RESULTS: Patients with MS had significantly lower values of AVP as compared to the normal subjects; 36 ± 5 cm/s vs 57 ± 5, p < 0.05, and lower FMD; 6% ± 1 vs 17 ± 3 p < 0.05 as well, there was significant correlations between AVP and FMD (r = 0.89, p < 0.001) 
520 |a CONCLUSION: Transthoracic echocardiographic determination of AVP is a simple practical method and correlates well with FMD in patients with MS 
650 4 |a Journal Article 
650 4 |a ALT, alanine transaminase 
650 4 |a AST, aspartate transaminase 
650 4 |a AVP 
650 4 |a AVP, aortic velocity propagation 
650 4 |a Aortic propagation velocity 
650 4 |a Arterial stiffness 
650 4 |a CRP, C reactive protein 
650 4 |a DBP, diastolic blood pressure 
650 4 |a E/e′, filling pressure 
650 4 |a EPF, epicardial fat 
650 4 |a FBS, fasting blood sugar 
650 4 |a FMD, flow mediated dilatation 
650 4 |a HDL, high density lipoprotein 
650 4 |a IVS, interventricular septum 
650 4 |a Metabolic syndrome 
650 4 |a SBP, systolic blood pressure 
650 4 |a TC, total cholesterol 
650 4 |a TG, triglycerides 
650 4 |a UA, uric acid 
650 4 |a WC, waist circumference 
700 1 |a ELSheikh, Ayman  |e verfasserin  |4 aut 
700 1 |a Sameer, Sameh  |e verfasserin  |4 aut 
700 1 |a Haseeb, Waiel  |e verfasserin  |4 aut 
700 1 |a ELSheikh, Eman  |e verfasserin  |4 aut 
700 1 |a Kheder, Lamia  |e verfasserin  |4 aut 
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773 1 8 |g volume:28  |g year:2016  |g number:4  |g day:28  |g month:10  |g pages:249-56 
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