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|a eng
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|a Zhang, Zhenyu
|e verfasserin
|4 aut
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|a Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids
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|c 2016
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|a Text
|b txt
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|a ƒaComputermedien
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|a Date Completed 21.06.2018
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|a Date Revised 21.06.2018
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Graphene oxide (GO) is a reliable and multifunctional platform to perform cell imaging. In this work, a controllable Pt-seed-mediated method is used to prepare GO/gold nanoparticle (AuNP) hybrids, and after the covalent binding of folic acid (FA), GO/AuNP/FA hybrids are prepared. Selective labeling and Raman imaging of folate receptor (FR)-positive HeLa cells are realized using such GO-based hybrids. In this system, FA is the targeting agent, AuNPs work as surface-enhanced Raman scattering substrates, and GO takes the role of both supporting the AuNPs with FA and acting as a Raman probe. This research further extends the application of GO as a multifunctional platform in bioimaging and other biomedical processes
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Wang, Meng
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|a Gao, Dongliang
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|a Luo, Da
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|a Liu, Qinghai
|e verfasserin
|4 aut
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|a Yang, Juan
|e verfasserin
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|a Li, Yan
|e verfasserin
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
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|g 32(2016), 40 vom: 11. Okt., Seite 10253-10258
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