|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM263715345 |
| 003 |
DE-627 |
| 005 |
20231224204515.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2016 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/acs.langmuir.6b02452
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0879.xml
|
| 035 |
|
|
|a (DE-627)NLM263715345
|
| 035 |
|
|
|a (NLM)27556595
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Cohen, Neta
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a pH and Salt Effects on Surface Activity and Self-Assembly of Copolymers Containing a Weak Polybase
|
| 264 |
|
1 |
|c 2016
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 06.06.2018
|
| 500 |
|
|
|a Date Revised 06.06.2018
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status PubMed-not-MEDLINE
|
| 520 |
|
|
|a Copolymers with well-defined architectures, controlled molecular weights, and narrow molar mass dispersities (Đ) were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization. The resultant polymers contain different combinations of the pH-responsive monomer 2-(diethylaminoethyl) methacrylate (DEAEMA), the hydrophobic comonomer butyl methacrylate (BMA), and a neutral hydrophilic stabilizing monomer polyethylene glycol monomethyl ether methacrylate (designated O950). Surface tension and cryo-TEM measurements of native and heavy-atom stained samples were used to characterize the pH and salt responsiveness of the different polymers as a function of their composition. These studies indicate that while the polymers predominately self-assemble to form spherical micelles, a narrow size distribution is observed in aqueous solutions of poly(O950)-b-(BMA) and poly(O950)-b-(DEAEMA-co-BMA), whereas a broad size distribution characterizes the assemblies of poly(O950)-b-(DEAEMA) and poly(DEAEMA-co-BMA). In the latter case, micelles having diameters around 15-25 nm are found along with smaller aggregates (about 10 nm) mostly arranged in elongated necklace-like structures. The pH and salt-responsiveness of the DEAEMA residue, as indicated by the surface activity of the copolymers, was found to depend on the nature of the additional components: covalently linked hydrophobic groups (BMA) moderated the pH response of the copolymer as compared to nonionic and hydrophilic groups as in poly(O950)-b-(DEAEMA). These results suggest that mutual interactions among the building blocks of self-assembling copolymers should be taken into account when designing responsive copolymers
|
| 650 |
|
4 |
|a Journal Article
|
| 700 |
1 |
|
|a Binyamin, Lana
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Levi-Kalisman, Yael
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Berguig, Geoffrey Y
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Convertine, Anthony
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Stayton, Patrick
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yerushalmi Rozen, Rachel
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 32(2016), 36 vom: 13. Sept., Seite 9286-92
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:32
|g year:2016
|g number:36
|g day:13
|g month:09
|g pages:9286-92
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/acs.langmuir.6b02452
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 32
|j 2016
|e 36
|b 13
|c 09
|h 9286-92
|