Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery

Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 39 vom: 04. Okt., Seite 8749-8754
1. Verfasser: Vyas, Vijay S (VerfasserIn)
Weitere Verfasser: Vishwakarma, Medhavi, Moudrakovski, Igor, Haase, Frederik, Savasci, Gökcen, Ochsenfeld, Christian, Spatz, Joachim P, Lotsch, Bettina V
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article covalent organic frameworks drug delivery molecular dynamics porous materials supramolecular chemistry Drug Carriers Imines Metal-Organic Frameworks Polymers mehr... Quercetin 9IKM0I5T1E
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferation studies indicate higher efficacy of the drug in cancer cells by nanocarrier delivery mediated by the COF
Beschreibung:Date Completed 08.11.2018
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201603006