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231224s2016 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20160707-07
|2 doi
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|a pubmed25n0875.xml
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|a eng
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| 100 |
1 |
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|a Pallado, Céline Mebsout
|e verfasserin
|4 aut
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| 245 |
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|a Progression of Macular Atrophy in Pattern Dystrophies
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 30.06.2017
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|a Date Revised 10.01.2018
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2016, SLACK Incorporated.
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|a BACKGROUND AND OBJECTIVE: To quantify the progression of macular atrophy associated with pattern dystrophies (PD)
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|a PATIENTS AND METHODS: Retrospective, observational study including patients with reticular PD and macular atrophy. A detailed ophthalmologic exam was performed, and progression of macular atrophy areas was evaluated on fundus autofluorescence frames using RegionFinder software, a semiautomated software embedded in Spectralis device (Heidelberg Engineering, Heidelberg, Germany)
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|a RESULTS: We included 19 eyes of 12 patients. The median follow-up was 4.5 years (interquartile range [IQR]: 2.7-5.5). Three eyes (16%) had choroidal neovascularization. Atrophy involved foveal area in 21% (four of 19) of cases. Decreased vision occurred in three eyes (16%). The median atrophy progression rate evaluated by RegionFinder software was 0.101 mm(2)/year (IQR: 0.054-0.257)
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|a CONCLUSION: The progression of macular atrophy in PDs appears to be relatively slow. Further studies are necessary to correlate the progression of atrophy in PDs with genetic data. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:652-658.]
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|a Journal Article
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|a Sikorav, Anne
|e verfasserin
|4 aut
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1 |
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|a Semoun, Oudy
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jung, Camille
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Souied, Eric H
|e verfasserin
|4 aut
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 47(2016), 7 vom: 01. Juli, Seite 652-8
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|x 2325-8179
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|g volume:47
|g year:2016
|g number:7
|g day:01
|g month:07
|g pages:652-8
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|u http://dx.doi.org/10.3928/23258160-20160707-07
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