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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1093/jxb/erw257
|2 doi
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|a pubmed24n1422.xml
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|a (NLM)27385766
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
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|a Feng, Jinlin
|e verfasserin
|4 aut
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|a Protein N-terminal acetylation is required for embryogenesis in Arabidopsis
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 06.11.2017
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|a Date Revised 29.05.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology.
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|a Early embryonic development generates precursors of all major cell types in Arabidopsis. Among these precursors, the hypophysis divides asymmetrically to form the progenitors of the quiescent center and columella stem cells. A great deal has been learnt about the mechanisms that control the asymmetric division of the hypophysis and embryogenesis at the transcriptional level; however, no evidence of regulation at the co- or post-translational level has been reported. Here, we show that mutation of the catalytic subunit (Naa10) or auxiliary subunit (Naa15) of NatA, an N-terminal acetyltransferase that catalyzes protein N-terminal acetylation, produces an embryo-lethal phenotype. In addition, Naa10 and Naa15 were found to interact physically in planta Further analysis revealed that the observed embryonic patterning defects started at the early globular stage and that the asymmetric division of the hypophysis was irregular; thus, no quiescent center progenitor cells were generated in naa10 and naa15 embryos. We further observed that the polar distributions of auxin and its efflux carrier PIN1 were disturbed in naa10 embryos. Our results suggest that NatA is required for asymmetric division of the hypophysis and early embryonic patterning in Arabidopsis, and provides a link between protein N-terminal acetylation and embryogenesis in plants
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Arabidopsis
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|a NatA
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|a asymmetric division
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|a embryogenesis
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|a hypophysis
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|a protein N-terminal acetylation.
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|a N-Terminal Acetyltransferases
|2 NLM
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| 650 |
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7 |
|a EC 2.3.1.88
|2 NLM
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| 700 |
1 |
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|a Li, Ruiqi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yu, Junya
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ma, Shuangshuang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wu, Chunyan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Cao, Ying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ma, Ligeng
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 67(2016), 15 vom: 07. Aug., Seite 4779-89
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
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| 773 |
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|g volume:67
|g year:2016
|g number:15
|g day:07
|g month:08
|g pages:4779-89
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|u http://dx.doi.org/10.1093/jxb/erw257
|3 Volltext
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|d 67
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|c 08
|h 4779-89
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