Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain

Bibliographische Detailangaben
Veröffentlicht in:	Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 36 vom: 28. Sept., Seite 7962-7969
1. Verfasser:	Kang, Jinyoung (VerfasserIn)
Weitere Verfasser:	Joo, Jinmyoung, Kwon, Ester J, Skalak, Matthew, Hussain, Sazid, She, Zhi-Gang, Ruoslahti, Erkki, Bhatia, Sangeeta N, Sailor, Michael J
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2016
Zugriff auf das übergeordnete Werk:	Advanced materials (Deerfield Beach, Fla.)
Schlagworte:	Journal Article gene knockdowns injured brains photoluminescence rabies virus glycoprotein peptides targeted nanoparticles Calcium Compounds RNA, Small Interfering Silicates calcium silicate mehr... S4255P4G5M Silicon Z4152N8IUI


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024	7		\|a 10.1002/adma.201600634 \|2 doi
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100	1		\|a Kang, Jinyoung \|e verfasserin \|4 aut
245	1	0	\|a Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain
264		1	\|c 2016
336			\|a Text \|b txt \|2 rdacontent
337			\|a ƒaComputermedien \|b c \|2 rdamedia
338			\|a ƒa Online-Ressource \|b cr \|2 rdacarrier
500			\|a Date Completed 10.10.2018
500			\|a Date Revised 04.04.2024
500			\|a published: Print-Electronic
500			\|a Citation Status MEDLINE
520			\|a © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
520			\|a Calcium ions react with silicic acid released from dissolving porous silicon nanoparticles to create an insoluble calcium silicate shell. The calcium silicate shell traps and protects an siRNA payload, which can be delivered to neuronal tissues in vitro or in vivo. Gene delivery is enhanced by the action of targeting and cell-penetrating peptides attached to the calcium silicate shell
650		4	\|a Journal Article
650		4	\|a gene knockdowns
650		4	\|a injured brains
650		4	\|a photoluminescence
650		4	\|a rabies virus glycoprotein peptides
650		4	\|a targeted nanoparticles
650		7	\|a Calcium Compounds \|2 NLM
650		7	\|a RNA, Small Interfering \|2 NLM
650		7	\|a Silicates \|2 NLM
650		7	\|a calcium silicate \|2 NLM
650		7	\|a S4255P4G5M \|2 NLM
650		7	\|a Silicon \|2 NLM
650		7	\|a Z4152N8IUI \|2 NLM
700	1		\|a Joo, Jinmyoung \|e verfasserin \|4 aut
700	1		\|a Kwon, Ester J \|e verfasserin \|4 aut
700	1		\|a Skalak, Matthew \|e verfasserin \|4 aut
700	1		\|a Hussain, Sazid \|e verfasserin \|4 aut
700	1		\|a She, Zhi-Gang \|e verfasserin \|4 aut
700	1		\|a Ruoslahti, Erkki \|e verfasserin \|4 aut
700	1		\|a Bhatia, Sangeeta N \|e verfasserin \|4 aut
700	1		\|a Sailor, Michael J \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Advanced materials (Deerfield Beach, Fla.) \|d 1998 \|g 28(2016), 36 vom: 28. Sept., Seite 7962-7969 \|w (DE-627)NLM098206397 \|x 1521-4095 \|7 nnns
773	1	8	\|g volume:28 \|g year:2016 \|g number:36 \|g day:28 \|g month:09 \|g pages:7962-7969
856	4	0	\|u http://dx.doi.org/10.1002/adma.201600634 \|3 Volltext
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