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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1093/jxb/erw249
|2 doi
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|a pubmed24n1346.xml
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|a (DE-627)NLM261605968
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|a (NLM)27325894
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Hassler, Sebastian
|e verfasserin
|4 aut
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| 245 |
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|a Function of the Golgi-located phosphate transporter PHT4;6 is critical for senescence-associated processes in Arabidopsis
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 06.11.2017
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|a Date Revised 25.03.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology.
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|a The phosphate transporter PHT4;6 locates to the trans-Golgi compartment, and its impaired activity causes altered intracellular phosphate compartmentation, leading to low cytosolic Pi levels, a blockage of Golgi-related processes such as protein glycosylation and hemicellulose biosynthesis, and a dwarf phenotype. However, it was unclear whether altered Pi homeostasis in pht4;6 mutants causes further cellular problems, typically associated with limited phosphate availability. Here we report that pht4;6 mutants exhibit a markedly increased disposition to induce dark-induced senescence. In control experiments, in which pht4;6 mutants and wild-type plants developed similarly, we confirmed that accelerated dark-induced senescence in mutants is not a 'pleiotropic' process associated with the dwarf phenotype. In fact, accelerated dark-induced senescence in pht4;6 mutants correlates strongly with increased levels of toxic NH4 (+) and higher sensitivity to ammonium, which probably contribute to the inability of pht4;6 mutants to recover from dark treatment. Experiments with modified levels of either salicylic acid (SA) or trans-zeatin (tZ) demonstrate that altered concentrations of these compounds in pht4;6 plants act as major cellular mediators for dark-induced senescence. This conclusion gained further support from the notion that the expression of the pht4;6 gene is, in contrast to genes coding for major phosphate importers, substantially induced by tZ. Taken together, our findings point to a critical function of PHT4;6 to control cellular phosphate levels, in particular the cytosolic Pi availability, required to energize plant primary metabolism for proper plant development. Phosphate and its allocation mediated by PHT4;6 is critical to prevent onset of dark-induced senescence
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Ammonium
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|a Golgi
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|a cytokinin
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|a phosphate
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|a salicylic acid
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|a senescence
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|a sugars.
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|a Arabidopsis Proteins
|2 NLM
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| 650 |
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|a Cytokinins
|2 NLM
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| 650 |
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|a PHT4;6 protein, Arabidopsis
|2 NLM
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| 650 |
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|a Phosphate Transport Proteins
|2 NLM
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| 650 |
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|a Chlorophyll
|2 NLM
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| 650 |
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|a 1406-65-1
|2 NLM
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| 700 |
1 |
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|a Jung, Benjamin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lemke, Lilia
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Novák, Ondřej
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Strnad, Miroslav
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Martinoia, Enrico
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Neuhaus, H Ekkehard
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 67(2016), 15 vom: 21. Aug., Seite 4671-84
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
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| 773 |
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|g volume:67
|g year:2016
|g number:15
|g day:21
|g month:08
|g pages:4671-84
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| 856 |
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|u http://dx.doi.org/10.1093/jxb/erw249
|3 Volltext
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|a AR
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|d 67
|j 2016
|e 15
|b 21
|c 08
|h 4671-84
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