Drosophila Torsin Protein Regulates Motor Control and Stress Sensitivity and Forms a Complex with Fragile-X Mental Retardation Protein

We investigated unknown in vivo functions of Torsin by using Drosophila as a model. Downregulation of Drosophila Torsin (DTor) by DTor-specific inhibitory double-stranded RNA (RNAi) induced abnormal locomotor behavior and increased susceptibility to H2O2. In addition, altered expression of DTor sign...

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Veröffentlicht in:Neural plasticity. - 1998. - 2016(2016) vom: 09., Seite 6762086
1. Verfasser: Nguyen, Phuong (VerfasserIn)
Weitere Verfasser: Seo, Jong Bok, Ahn, Hyo-Min, Koh, Young Ho
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Drosophila Proteins Molecular Chaperones TOR1A protein, human Fragile X Mental Retardation Protein 139135-51-6 target of rapamycin protein, Drosophila EC 2.7.1.- TOR Serine-Threonine Kinases EC 2.7.11.1