|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM261435906 |
| 003 |
DE-627 |
| 005 |
20231224195539.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2016 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/acs.langmuir.6b00488
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0871.xml
|
| 035 |
|
|
|a (DE-627)NLM261435906
|
| 035 |
|
|
|a (NLM)27307097
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Baccile, Niki
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a pH-Driven Self-Assembly of Acidic Microbial Glycolipids
|
| 264 |
|
1 |
|c 2016
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 18.09.2018
|
| 500 |
|
|
|a Date Revised 04.10.2018
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Microbial glycolipids are a class of well-known compounds, but their self-assembly behavior is still not well understood. While the free carboxylic acid end group makes some of them interesting stimuli-responsive compounds, the sugar hydrophilic group and the nature of the fatty acid chain make the understanding of their self-assembly behavior in water not easy and highly unpredictable. Using cryo-transmission electron microscopy (cryo-TEM) and both pH-dependent in situ and ex situ small angle X-ray scattering (SAXS), we demonstrate that the aqueous self-assembly at room temperature (RT) of a family of β-d-glucose microbial glycolipids bearing a saturated and monounsaturated C18 fatty acid chain cannot be explained on the simple basis of the well-known packing parameter. Using the "pH-jump" process, we find that the molecules bearing a monosaturated fatty acid forms vesicles below pH 6.2, as expected, but the derivative with a saturated fatty acid forms infinite bilayer sheets below pH 7.8, instead of vesicles. We show that this behavior can be explained on the different bilayer membrane elasticity as a function of temperature. Membranes are either flexible or stiff for experiments performed at a temperature respectively above or below the typical melting point, TM, of the lipidic part of each compound. Finally, we also show that the disaccharide-containing acidic cellobioselipid forms a majority of chiral fibers, instead of the expected micelles
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a Acids
|2 NLM
|
| 650 |
|
7 |
|a Glycolipids
|2 NLM
|
| 650 |
|
7 |
|a Micelles
|2 NLM
|
| 650 |
|
7 |
|a Cellobiose
|2 NLM
|
| 650 |
|
7 |
|a 16462-44-5
|2 NLM
|
| 700 |
1 |
|
|a Selmane, Mohamed
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Le Griel, Patrick
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Prévost, Sylvain
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Perez, Javier
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Stevens, Christian V
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Delbeke, Elisabeth
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zibek, Susanne
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Guenther, Michael
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Soetaert, Wim
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Van Bogaert, Inge N A
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Roelants, Sophie
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 32(2016), 25 vom: 28. Juni, Seite 6343-59
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:32
|g year:2016
|g number:25
|g day:28
|g month:06
|g pages:6343-59
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/acs.langmuir.6b00488
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 32
|j 2016
|e 25
|b 28
|c 06
|h 6343-59
|