Activatable Fluorescent Nanoprobe with Aggregation-Induced Emission Characteristics for Selective In Vivo Imaging of Elevated Peroxynitrite Generation

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 33 vom: 15. Sept., Seite 7249-56
Auteur principal: Song, Zhegang (Auteur)
Autres auteurs: Mao, Duo, Sung, Simon H P, Kwok, Ryan T K, Lam, Jacky W Y, Kong, Deling, Ding, Dan, Tang, Ben Zhong
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Journal Article activatable fluorescent probes aggregation-induced emission elevated peroxynitrite generation inflammation nanoprobes
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520 |a An activatable fluorescent nanoprobe with aggregation-induced emission signature is developed. The nanoprobe is nonfluorescent, but can be induced to emit intensely after reaction with peroxynitrite forming an intramolecular hydrogen bond. Excellent performance for selective in vivo imaging of inflammation with elevated peroxynitrite generation and efficient visualization of in vivo treatment efficacy of anti-inflammatory agents is demonstrated 
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700 1 |a Sung, Simon H P  |e verfasserin  |4 aut 
700 1 |a Kwok, Ryan T K  |e verfasserin  |4 aut 
700 1 |a Lam, Jacky W Y  |e verfasserin  |4 aut 
700 1 |a Kong, Deling  |e verfasserin  |4 aut 
700 1 |a Ding, Dan  |e verfasserin  |4 aut 
700 1 |a Tang, Ben Zhong  |e verfasserin  |4 aut 
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