Synthesis of 8-oxo-7,8-dihydro-2'-deoxyguanosine from 2'-deoxyguanosine using Cu(II)/H2O2/ascorbate : A new strategy for an improved yield
The free nucleoside 2'-deoxyguanosine (dGuo) is the most susceptible to oxidation by reactive oxygen species (ROS) compared to the other free nucleosides, and its oxidation product 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) has been used as a biomarker to quantify oxidative stress dam...
| Veröffentlicht in: | BioTechniques. - 1991. - 60(2016), 6 vom: 01., Seite 279-84 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | BioTechniques |
| Schlagworte: | Journal Article 8-oxodGuo DNA damage Fenton reaction dGuo synthesis Metals Copper 789U1901C5 8-Hydroxy-2'-Deoxyguanosine mehr... |
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