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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201601030
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|a eng
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|a Nonoyama, Takayuki
|e verfasserin
|4 aut
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|a Double-Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration
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|c 2016
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|a Text
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|a ƒaComputermedien
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|a Date Completed 08.10.2018
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|a Date Revised 22.02.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2016 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a On implanting hydroxyapatite-mineralized tough hydrogel into osteochondral defects of rabbits, osteogenesis spontaneously penetrates into the gel matrix owing to the semi-permeablility of the hydrogel. The gradient layer (around 40 μm thick) contributes quite strong bonding of the gel to bone. This is the first success in realizing the robust osteointegration of tough hydrogels, and the method is simple and feasible for practical use
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|a Evaluation Study
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|a Journal Article
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|a biomaterials
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|a double-network hydrogels
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|a hydroxyapatite
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|a osteointegration
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|a semi-permeability
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|a Hydrogels
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|a Durapatite
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|a Wada, Susumu
|e verfasserin
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|a Kiyama, Ryuji
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|a Kitamura, Nobuto
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|4 aut
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|a Mredha, Md Tariful Islam
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|a Zhang, Xi
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|a Kurokawa, Takayuki
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|a Nakajima, Tasuku
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|4 aut
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|a Takagi, Yasuaki
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|a Yasuda, Kazunori
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|a Gong, Jian Ping
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|t Advanced materials (Deerfield Beach, Fla.)
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|g 28(2016), 31 vom: 17. Aug., Seite 6740-5
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|g volume:28
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