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231224s2016 xx |||||o 00| ||eng c |
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7 |
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|a 10.3928/23258160-20160419-03
|2 doi
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|a eng
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| 100 |
1 |
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|a Adhi, Mehreen
|e verfasserin
|4 aut
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| 245 |
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|a Application of Novel Software Algorithms to Spectral-Domain Optical Coherence Tomography for Automated Detection of Diabetic Retinopathy
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 26.06.2017
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|a Date Revised 01.12.2017
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2016, SLACK Incorporated.
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|a BACKGROUND AND OBJECTIVE: To present novel software algorithms applied to spectral-domain optical coherence tomography (SD-OCT) for automated detection of diabetic retinopathy (DR)
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|a PATIENTS AND METHODS: Thirty-one diabetic patients (44 eyes) and 18 healthy, nondiabetic controls (20 eyes) who underwent volumetric SD-OCT imaging and fundus photography were retrospectively identified. A retina specialist independently graded DR stage. Trained automated software generated a retinal thickness score signifying macular edema and a cluster score signifying microaneurysms and/or hard exudates for each volumetric SD-OCT
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|a RESULTS: Of 44 diabetic eyes, 38 had DR and six eyes did not have DR. Leave-one-out cross-validation using a linear discriminant at missed detection/false alarm ratio of 3.00 computed software sensitivity and specificity of 92% and 69%, respectively, for DR detection when compared to clinical assessment
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|a CONCLUSION: Novel software algorithms applied to commercially available SD-OCT can successfully detect DR and may have potential as a viable screening tool for DR in future. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:410-417.]
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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1 |
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|a Semy, Salim K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Stein, David W
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Potter, Daniel M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kuklinski, Walter S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sleeper, Harry A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Duker, Jay S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Waheed, Nadia K
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 47(2016), 5 vom: 01. Mai, Seite 410-7
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnns
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| 773 |
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|g volume:47
|g year:2016
|g number:5
|g day:01
|g month:05
|g pages:410-7
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