Drug Delivery : Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery (Adv. Mater. 16/2016)

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 16 vom: 23. Apr., Seite 3223
1. Verfasser: Ye, Yanqi (VerfasserIn)
Weitere Verfasser: Yu, Jicheng, Wang, Chao, Nguyen, Nhu-Y, Walker, Glenn M, Buse, John B, Gu, Zhen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article diabetes drug delivery microneedles pancreatic cells physiological signals
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A bio-responsive microneedle-based patch, integrated with a rhodamine-stained glucose-signal amplifier and calcein-AM-stained pancreatic β-cell capsules, is developed by Z. Gu and co-workers. This "smart cell patch", described on page 3115, effectively regulates the blood glucose level of type-1 diabetic mice, achieving a reduction for over 10 h. Image credit: Yanqi Ye
Beschreibung:Date Revised 30.09.2020
published: Print
Citation Status PubMed-not-MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201670112