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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1016/j.plantsci.2016.03.007
|2 doi
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|a pubmed25n0865.xml
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|a (NLM)27095401
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|a (PII)S0168-9452(16)30038-3
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Rogato, Alessandra
|e verfasserin
|4 aut
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|a Down-regulated Lotus japonicus GCR1 plants exhibit nodulation signalling pathways alteration
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 14.12.2016
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
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|a G Protein Coupled Receptor (GPCRs) are integral membrane proteins involved in various signalling pathways by perceiving many extracellular signals and transducing them to heterotrimeric G proteins, which further transduce these signals to intracellular downstream effectors. GCR1 is the only reliable plant candidate as a member of the GPCRs superfamily. In the legume/rhizobia symbiotic interaction, G proteins are involved in signalling pathways controlling different steps of the nodulation program. In order to investigate the putative hierarchic role played by GCR1 in these symbiotic pathways we identified and characterized the Lotus japonicus gene encoding the seven transmembrane GCR1 protein. The detailed molecular and topological analyses of LjGCR1 expression patterns that are presented suggest a possible involvement in the early steps of nodule organogenesis. Furthermore, phenotypic analyses of independent transgenic RNAi lines, showing a significant LjGCR1 expression down regulation, suggest an epistatic action in the control of molecular markers of nodulation pathways, although no macroscopic symbiotic phenotypes could be revealed
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a G proteins
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|a GCR1
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|a Nodule organogenesis
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|a Signalling
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|a Symbiotic-nitrogen-fixation
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|a Plant Proteins
|2 NLM
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|a Receptors, G-Protein-Coupled
|2 NLM
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|a Valkov, Vladimir Totev
|e verfasserin
|4 aut
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|a Alves, Ludovico Martins
|e verfasserin
|4 aut
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|a Apone, Fabio
|e verfasserin
|4 aut
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|a Colucci, Gabriella
|e verfasserin
|4 aut
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|a Chiurazzi, Maurizio
|e verfasserin
|4 aut
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|i Enthalten in
|t Plant science : an international journal of experimental plant biology
|d 1985
|g 247(2016) vom: 11. Juni, Seite 71-82
|w (DE-627)NLM098174193
|x 1873-2259
|7 nnns
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|g volume:247
|g year:2016
|g day:11
|g month:06
|g pages:71-82
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|u http://dx.doi.org/10.1016/j.plantsci.2016.03.007
|3 Volltext
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|d 247
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