Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions

In vitro-derived platelets (PLTs), which could provide an alternative source of PLTs for patient transfusions, are formed from polyploid megakaryocytes (MKs) that extend long cytoplasmic projections, termed proplatelets (proPLTs). In this study, we compared polyploidization and proPLT formation (PPF...

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Veröffentlicht in:Biochemical engineering journal. - 1998. - 111(2016) vom: 15. Juli, Seite 24-33
1. Verfasser: Schlinker, Alaina C (VerfasserIn)
Weitere Verfasser: Duncan, Mark T, DeLuca, Teresa A, Whitehead, David C, Miller, William M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Biochemical engineering journal
Schlagworte:Journal Article Culture-derived platelets animal cell culture biomedical cell adhesion physiology tissue culture