Choroidal Thickness and En Face Optical Coherence Tomography Imaging in Autoimmune Retinopathy

Copyright 2016, SLACK Incorporated.

Détails bibliographiques
Publié dans:Ophthalmic surgery, lasers & imaging retina. - 2013. - 47(2016), 4 vom: 01. Apr., Seite 362-5
Auteur principal: Polascik, Breanna A (Auteur)
Autres auteurs: Grewal, Dilraj S, Jiramongkolchai, Kim, Fekrat, Sharon
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Ophthalmic surgery, lasers & imaging retina
Sujets:Case Reports Journal Article Research Support, Non-U.S. Gov't Autoantigens Biomarkers Eye Proteins Heat-Shock Proteins Retinol-Binding Proteins interstitial retinol-binding protein
Description
Résumé:Copyright 2016, SLACK Incorporated.
A 57-year-old white woman developed autoimmune retinopathy (AIR) in both eyes associated with bilateral autoimmune sensorineural hearing loss. Laboratory testing was positive for 68kDa (heat-shock protein) and 136kDa (human interstitial retinoid-binding protein). Extensive cancer screening was negative. Spectral-domain optical coherence tomography enhanced depth imaging demonstrated a markedly thickened choroid in both eyes. En face imaging showed a distinctive pattern of granular hyperreflective foveal dots. The concurrent sensorineural hearing loss was thought to be of autoimmune origin and also responded to immunosuppressive treatment. Eyes with non-paraneoplastic, seropositive AIR may have associated increased choroidal thickness. Audiology testing should be considered
Description:Date Completed 13.12.2016
Date Revised 30.12.2016
published: Print
Citation Status MEDLINE
ISSN:2325-8179
DOI:10.3928/23258160-20160324-10