Choroidal Thickness and En Face Optical Coherence Tomography Imaging in Autoimmune Retinopathy
Copyright 2016, SLACK Incorporated.
Publié dans: | Ophthalmic surgery, lasers & imaging retina. - 2013. - 47(2016), 4 vom: 01. Apr., Seite 362-5 |
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Auteur principal: | |
Autres auteurs: | , , |
Format: | Article en ligne |
Langue: | English |
Publié: |
2016
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Accès à la collection: | Ophthalmic surgery, lasers & imaging retina |
Sujets: | Case Reports Journal Article Research Support, Non-U.S. Gov't Autoantigens Biomarkers Eye Proteins Heat-Shock Proteins Retinol-Binding Proteins interstitial retinol-binding protein |
Résumé: | Copyright 2016, SLACK Incorporated. A 57-year-old white woman developed autoimmune retinopathy (AIR) in both eyes associated with bilateral autoimmune sensorineural hearing loss. Laboratory testing was positive for 68kDa (heat-shock protein) and 136kDa (human interstitial retinoid-binding protein). Extensive cancer screening was negative. Spectral-domain optical coherence tomography enhanced depth imaging demonstrated a markedly thickened choroid in both eyes. En face imaging showed a distinctive pattern of granular hyperreflective foveal dots. The concurrent sensorineural hearing loss was thought to be of autoimmune origin and also responded to immunosuppressive treatment. Eyes with non-paraneoplastic, seropositive AIR may have associated increased choroidal thickness. Audiology testing should be considered |
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Description: | Date Completed 13.12.2016 Date Revised 30.12.2016 published: Print Citation Status MEDLINE |
ISSN: | 2325-8179 |
DOI: | 10.3928/23258160-20160324-10 |