Chondroitin 6-Sulfation Regulates Perineuronal Net Formation by Controlling the Stability of Aggrecan

Perineuronal nets (PNNs) are lattice-like extracellular matrix structures composed of chondroitin sulfate proteoglycans (CSPGs). The appearance of PNNs parallels the decline of neural plasticity, and disruption of PNNs reactivates neural plasticity in the adult brain. We previously reported that sul...

Description complète

Détails bibliographiques
Publié dans:Neural plasticity. - 1998. - 2016(2016) vom: 08., Seite 1305801
Auteur principal: Miyata, Shinji (Auteur)
Autres auteurs: Kitagawa, Hiroshi
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Neural plasticity
Sujets:Journal Article Research Support, Non-U.S. Gov't Aggrecans Chondroitin Sulfates 9007-28-7 Sulfotransferases EC 2.8.2.- ADAMTS Proteins EC 3.4.24.-