Chondroitin 6-Sulfation Regulates Perineuronal Net Formation by Controlling the Stability of Aggrecan

Perineuronal nets (PNNs) are lattice-like extracellular matrix structures composed of chondroitin sulfate proteoglycans (CSPGs). The appearance of PNNs parallels the decline of neural plasticity, and disruption of PNNs reactivates neural plasticity in the adult brain. We previously reported that sul...

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Veröffentlicht in:Neural plasticity. - 1998. - 2016(2016) vom: 08., Seite 1305801
1. Verfasser: Miyata, Shinji (VerfasserIn)
Weitere Verfasser: Kitagawa, Hiroshi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Aggrecans Chondroitin Sulfates 9007-28-7 Sulfotransferases EC 2.8.2.- ADAMTS Proteins EC 3.4.24.-