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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1016/j.jsha.2015.07.003
|2 doi
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|a pubmed24n1418.xml
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|a (DE-627)NLM259166146
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|a (NLM)27053895
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Salvatore, Azzarelli
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Usefulness of SYNTAX score II in complex percutaneous coronary interventions in the setting of acute coronary syndrome
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 07.04.2016
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|a Date Revised 25.05.2024
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a BACKGROUND: SYNTAX score II (SS II) integrates anatomical SS with clinical characteristics allowing an individualized prediction of long-term mortality
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|a AIMS: We sought to assess to evaluate the usefulness of SS II in a real-world acute coronary syndromes (ACS) population with severe coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI)
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|a METHODS: From August 2011 to May 2013, out of 1591 consecutive patients admitted for ACS, 217 (13.6%) showed severe CAD (three-vessel disease and/or left main involvement). Among the latter, 100 patients underwent PCI and were enrolled into the study. SS II was calculated in all patients. One-year clinical follow-up was performed; major adverse cardiac and cerebrovascular events (MACCE) were defined as a composite of death, nonfatal myocardial infarction, stroke, or repeat revascularization
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| 520 |
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|a RESULTS: The median SS II was 29 (range, 14-59). Overall, MACCE occurred in 25% of patients (cardiac death 4%, myocardial infarction 4%, stroke 0%, and repeat revascularization 17%). The 1-year MACCE-free survival was significantly lower in patients with SS (⩾29), than in those with SS II (<29) (64.2% vs. 87.2%, respectively; p = 0.007). In multivariate Cox regression analysis, the presence of unprotected left main stenosis [hazard ratio 2.52, 95% confidence interval (CI): 1.02-5.85; p = 0.031] and SS II ⩾29 (hazard ratio 2.74, 95% CI: 1.30-8.21; p = 0.011) were the only predictors of MACCE at 1-year clinical follow-up. The c-index of SS score II was 0.70 (95% CI: 0.58-0.81). For patients who experienced MACCE, the SS II reclassification improved by 36%, while in nonevent patients the reclassification improved by 22%. The net reclassification index was 0.24 (p = 0.09)
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|a CONCLUSION: SS II might represent a useful tool to predict clinical events in not only ideal stable patients, but also an unrestricted, real world population of patients with ACS and severe CAD undergoing PCI
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|a Journal Article
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|a Acute coronary syndrome
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|a Percutaneous coronary intervention
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| 650 |
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|a Severe coronary artery disease
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| 650 |
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4 |
|a Syntax score II
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| 700 |
1 |
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|a Boukhris, Marouane
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Giubilato, Simona
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tomasello, Salvatore Davide
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Castaing, Marine
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Giunta, Rocco
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Marzà, Francesco
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Abdelbasset, Hosam Mohamad
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Khamis, Hazem
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Galassi, Alfredo Ruggero
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of the Saudi Heart Association
|d 1999
|g 28(2016), 2 vom: 15. Apr., Seite 63-72
|w (DE-627)NLM098225227
|x 1016-7315
|7 nnns
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| 773 |
1 |
8 |
|g volume:28
|g year:2016
|g number:2
|g day:15
|g month:04
|g pages:63-72
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| 856 |
4 |
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|u http://dx.doi.org/10.1016/j.jsha.2015.07.003
|3 Volltext
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|h 63-72
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